Kiss2 peptide (acetate)
Product Specifications
UNSPSC Description
Kiss2 peptide acetate is the acetate form of Kiss2 pepride (HY-P10256). Kiss2 peptide acetate is a positive regulator of reproduction. Kiss2 peptide acetate binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc)[1].
Target Antigen
Kisspeptin Receptor; PKA; PKC
Type
Peptides
Related Pathways
Epigenetics;GPCR/G Protein;Stem Cell/Wnt;TGF-beta/Smad
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/kiss2-peptide-acetate.html
Purity
99.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)CC1=CC=CC=C1)N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CC4=CC=CC=C4)=O)CCC2)=O)CC(N)=O)=O)CC5=CC=CC=C5)=O)CC(N)=O.CC(O)=O.[x]
Molecular Weight
1257.44 (free base)
References & Citations
[1]Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10256A/Kiss2-peptide-acetate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10256A/
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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