SR-3-65
SR-3-65 (compound 6) is a Indisulam derivative, and inhibits the migration of gastric cancer cells. SR-3-65 attenuates PI3K/AKT/GSK-3β/β-catenin signaling pathway[1].
Product Specifications
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sr-3-65.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=CC(C#N)=C1)(NC2=CC(C(F)(F)F)=CC3=C2NC=C3Cl)=O
Molecular Formula
C16H9ClF3N3O2S
Molecular Weight
399.77
References & Citations
[1]Hou C, et al. Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells. Biomed Pharmacother. 2024;172:116259.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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