ADH-353
ADH-353 can inhibit Aβ fibrillation and reduce Aβ-induced cytotoxicity in SH-SY5Y and N2a cells. ADH-353 can be used in Alzheimer's disease-related research[1].
Product Specifications
CAS Number
2711712-81-9
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/adh-353.html
Smiles
O=C(C1=CC(NC(C2=CC(NC(C3=CC([N+]([O-])=O)=CN3CCCN)=O)=CN2CCCN)=O)=CN1CCCC)OCC
Molecular Formula
C27H38N8O6
Molecular Weight
570.64
References & Citations
[1]Dabas A, et al. Structural Reorganization Mechanism of the Aβ42 Fibril Mediated by N-Substituted Oligopyrrolamide ADH-353. ACS Chem Neurosci. 2024 Sep 4;15 (17) :3136-3151.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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