Rapacuronium bromide

Rapacuronium bromide (Org 9487), a non-depolarizing neuromuscular blocker, is an allosteric modulator of muscarinic acetylcholine receptor (mAChR) [1].

Product Specifications

CAS Number

[156137-99-4]

Product Name Alternative

Org 9487

UNSPSC

12352005

Hazard Statement

H302, H312, H331

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/RAPACURONIUM_BROMIDE.html

Purity

98.0

Solubility

DMSO : ≥ 125 mg/mL

Smiles

C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])C[C@H]([N+]5(CC=C)CCCCC5)[C@@H]4OC(CC)=O)([H])C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C1.[Br-]

Molecular Formula

C37H61BrN2O4

Molecular Weight

677.80

Precautions

H302, H312, H331

References & Citations

[1]Jakubík J, et al. Divergence of allosteric effects of Rapacuronium on binding and function of muscarinic receptors. BMC Pharmacol. 2009 Dec 28;9:15.|[2]Vizi ES, et al. A new short-acting non-depolarizing muscle relaxant (SZ1677) without cardiovascular side-effects. Acta Anaesthesiol Scand. 2003 Mar;47 (3) :291-300.