Prolyl Endopeptidase Inhibitor 1

Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potent prolyl endopeptidase (PEP; PE) inhibitor, with a Ki value of 15 nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect[1].

Product Specifications

CAS Number

[86925-97-5]

Product Name Alternative

Boc-Pro-prolinal; (Boc) -Prolyl-prolinal

UNSPSC

12352005

Target

Prolyl Endopeptidase (PREP)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/prolyl-endopeptidase-inhibitor-1.html

Concentration

10mM

Purity

98.34

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1[C@H](C(N2[C@H](C=O)CCC2)=O)CCC1)OC(C)(C)C

Molecular Formula

C15H24N2O4

Molecular Weight

296.36

References & Citations

[1]Yoshimoto T, et al. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect. J Pharmacobiodyn. 1987 Dec;10 (12) :730-5.|[2]Yoshimoto T, et al. Comparison of inhibitory effects of prolinal-containing peptide derivatives on prolyl endopeptidases from bovine brain and Flavobacterium. J Biochem. 1985 Oct;98 (4) :975-9.