Periglaucine B
Periglaucine B ((+) -Periglaucine B) is an alkaloid and an HBsAg inhibitor. Periglaucine B can be isolated from Pericampylus glaucus. Periglaucine B inhibits the secretion of hepatitis B virus (HBV) surface antigen (HBsAg) in Hep G2.2.15 cells with an IC50 of 0.47 mM[1].
Product Specifications
CAS Number
1025023-05-5
Product Name Alternative
(+) -Periglaucine B
UNSPSC
12352005
Target
HBV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/periglaucine-b.html
Solubility
10 mM in DMSO
Smiles
CO[C@]1(O[C@@]([H])(C2)C3=CC4=C(OCO4)C=C3[C@@](CC5=O)(CC6)[C@]12N6C)[C@H]5OC
Molecular Formula
C20H23NO6
Molecular Weight
373.40
References & Citations
[1]Yan MH, et al. Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus. J Nat Prod. 2008 May;71 (5) :760-3.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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