cIAP1 Ligand-Linker Conjugates 8
Product Specifications
Product Name Alternative
E3 ligase Ligand-Linker Conjugates 46
UNSPSC Description
cIAP1 Ligand-Linker Conjugates 8 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 8 can be used to design SNIPERs[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-46.html
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOCCNC([C@H](NC([C@H](O)[C@@H](NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)CC4=CC=CC=C4)=O)CC(C)C)=O
Molecular Weight
704.85
References & Citations
[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-128825/cIAP1-Ligand-Linker-Conjugates-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-128825/
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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