Glycolithocholic acid 3-sulfate

Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease[1][2].

Product Specifications

CAS Number

[15324-64-8]

Product Name Alternative

Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG

UNSPSC

12352211

Target

Endogenous Metabolite; HIV

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/glycolithocholic-acid-3-sulfate.html

Purity

99.21

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@@]([H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[C@]3([C@]([H])(CC1)[C@@]4([C@]([H])(CC3)C[C@@H](CC4)OS(=O)(O)=O)C)[H]

Molecular Formula

C26H43NO7S

Molecular Weight

513.69

References & Citations

[1]Baba M, et al. Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro. J Acquir Immune Defic Syndr (1988) . 1989;2 (3) :264-71.|[2]Yousef IM, et al. Lithocholate cholestasis--sulfated glycolithocholate-induced intrahepatic cholestasis in rats. Gastroenterology. 1981 Feb;80 (2) :233-41.