Vutrisiran
Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR) -mediated amyloidosis research[1].
Product Specifications
CAS Number
[1867157-35-4]
Product Name Alternative
ALN-TTRsc02
UNSPSC
12352208
Target
Small Interfering RNA (siRNA) ; Transthyretin (TTR)
Type
Oligonucleotides
Related Pathways
Epigenetics; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vutrisiran.html
Purity
97.37
Solubility
H2O : ≥ 20 mg/mL
Smiles
[Vutrisiran]
Molecular Formula
C530H715F9N171O323P43S6
Molecular Weight
16345.00
References & Citations
[1]Bahru A Habtemariam, et al. Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects. Clin Pharmacol Ther. 2021 Feb;109 (2) :372-382.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Available Sizes
Curated Selection
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