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Vutrisiran

Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR) -mediated amyloidosis research[1].

Product Specifications

CAS Number

[1867157-35-4]

Product Name Alternative

ALN-TTRsc02

UNSPSC

12352208

Target

Small Interfering RNA (siRNA) ; Transthyretin (TTR)

Type

Oligonucleotides

Related Pathways

Epigenetics; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/vutrisiran.html

Purity

97.37

Solubility

H2O : ≥ 20 mg/mL

Smiles

[Vutrisiran]

Molecular Formula

C530H715F9N171O323P43S6

Molecular Weight

16345.00

References & Citations

[1]Bahru A Habtemariam, et al. Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects. Clin Pharmacol Ther. 2021 Feb;109 (2) :372-382.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-132589/Vutrisiran-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-132589/Vutrisiran-SDS-MedChemExpress.pdf

Scientific Category

Oligonucleotides

Clinical Information

Phase 3

Available Sizes

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