(Des-Gly10, D-Ala6, Pro-NHEt9) -LHRH

(Des-Gly10, D-Ala6, Pro-NHEt9) -LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH) . (Des-Gly10, D-Ala6, Pro-NHEt9) -LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10, D-Ala6, Pro-NHEt9) -LHRH has potential applications in biochemical analysis and fertility[1][2][3].

Product Specifications

CAS Number

[52435-06-0]

Product Name Alternative

Surfagon

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

GnRH Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/des-gly10-d-ala6-pro-nhet9-lhrh.html

Purity

99.53

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N3[C@@H](CCC3)C(NCC)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)CC5=CNC6=CC=CC=C56)=O

Molecular Formula

C56H78N16O12

Molecular Weight

1167.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Wan B, et al. Polymer source affects in vitro-in vivo correlation of leuprolide acetate PLGA microspheres. Int J Pharm. 2022 Sep 25;625:122032.|[2]Masalova OO, et al. Effect of Surfagon on Open Field and Elevated Plus Maze Behavior of Gonadectomized and Non-Gonadectomized Male Rats. Bull Exp Biol Med. 2019 Nov;168 (1) :52-54.|[3]Kraevskiy A Y, et al. Surfagon and Ketaprofen for increasing fertility and preventing embryonic death in cows after insemination AY[J]. Ukrainian Journal of Ecology, 2020, 10 (4) : 159-164.