Nornidulin
Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC=2 μg/mL) .2 Nornidulin has cytotoxic activity in MOLT-3 cells (IC50=35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s=>116.4 μM) .
Product Specifications
CAS Number
[33403-37-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nornidulin.html
Purity
99.30
Smiles
CC1=C(C(Cl)=C(C2=C1OC(C3=C(O2)C(Cl)=C(C(Cl)=C3C)O)=O)/C(C)=C\C)O
Molecular Formula
C19H15Cl3O5
Molecular Weight
429.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Dean, et al. Nidulin and “Ustin”: Two chlorine-containing metabolic products of Aspergillus nidulans. Nature 172 (4372), 344 (1953) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
