Nornidulin
Product Specifications
UNSPSC Description
Nornidulin is a depsidone originally isolated from A. nidulans that has antibacterial activity against M. tuberculosis and M. ranoe as well as antifungal activity against T. tonsurans and M. audouini. It also inhibits the growth of methicillin-resistant S. aureus (MRSA; MIC=2 μg/mL).2 Nornidulin has cytotoxic activity in MOLT-3 cells (IC50=35.7 μM) but not HuCCA-1, HepG2, or A549 cells (IC50s=>116.4 μM).
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nornidulin.html
Smiles
CC1=C(C(Cl)=C(C2=C1OC(C3=C(O2)C(Cl)=C(C(Cl)=C3C)O)=O)/C(C)=C\C)O
Molecular Weight
429.68
References & Citations
[1]Dean, et al. Nidulin and “Ustin”: Two chlorine-containing metabolic products of Aspergillus nidulans. Nature 172(4372), 344 (1953).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119631/Nornidulin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119631/
Clinical Information
No Development Reported
CAS Number
33403-37-1
Curated Selection
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