UBE2B rabbit pAb
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P63146
Swiss Prot
P63146
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human UBE2B AA range: 23-73
Target
UBE2B
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane . Nucleus . In peripheral neurons, expressed both at the plasma membrane and in nuclei. .
Gene ID (Human)
7320
Available Sizes
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