Buforin II

Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. Buforin II has antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria[1].

Product Specifications

CAS Number

[172998-24-2]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/buforin-ii.html

Purity

98.61

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

NCCCC[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC=N1)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](C(C)C)NC([C@H]2N(C([C@H](CC3=CC=CC=C3)NC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H]([C@H](O)C)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C106H184N40O26

Molecular Weight

2434.85

References & Citations

[1]Oscar Cirioni, et al. Therapeutic efficacy of buforin II and rifampin in a rat model of Acinetobacter baumannii sepsis. Crit Care Med. 2009 Apr;37 (4) :1403-7.