Carbonic anhydrase inhibitor 22

Carbonic anhydrase inhibitor 22 (Compd 2g), a sulfonamide carbonic anhydrase inhibitor, with Ki values of 762 nM (hCA I), 20.3 nM (hCA II), 8.3 nM (hCA VII), 17.9 nM (hCA IX) and 10.5 nM (hCA XII), repectively[1].

Product Specifications

CAS Number

[146533-50-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-22.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(OCC2=CC=CC=C2)C=C1)(N)=O

Molecular Formula

C13H13NO3S

Molecular Weight

263.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Fabrizio Carta, et al. A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorg Med Chem. 2015 Apr 15;23 (8) :1828-40.