M-PEG-thiol (MW 1000)

M-PEG-thiol (MW 1000) is a surface modifier that can modify DNA thiolation and is used in the synthesis of gold nanorods (AuNR) . m-PEG-thiol (MW 1000) can load thiolated DNA onto AuNR, form a covalent bond with the surface of gold nanoparticles through the thiol group, and stabilize the nanoparticles by the steric hindrance effect of the polyethylene glycol chain, preventing aggregation and enhancing its biocompatibility. m-PEG-thiol (MW 1000) can also provide a platform for the subsequent coupling of biomolecules (such as DNA, antibodies) by replacing surfactants (such as CTAB) on the surface of nanoparticles, thereby exerting its activity in promoting the functionalization of nanomaterials[1][2].

Product Specifications

CAS Number

[134874-49-0]

Product Name Alternative

MPEG-SH (MW 1000)

UNSPSC

12352200

Hazard Statement

H315, H319, H335, H372, H410

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/m-peg-thiol-mw-1000.html

Purity

98.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

SCCOCCOC.[n]

Molecular Formula

(C2H4O) nC3H8OS

Molecular Weight

1000 (Average)

Precautions

H315, H319, H335, H372, H410

References & Citations

[1]Li J, et al. Simple and Rapid Functionalization of Gold Nanorods with Oligonucleotides Using an mPEG-SH/Tween 20-Assisted Approach. Langmuir. 2015 Jul 21;31 (28) :7869-76.|[2]Kincanon M, et al. Nanoparticle Size Influences the Self-Assembly of Gold Nanorods Using Flexible Streptavidin-Biotin Linkages. ACS Nano. 2023 Dec 12;17 (23) :24090-24103.