Br-C10-methyl ester
Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432) . PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein[1].
Product Specifications
CAS Number
[6287-90-7]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/br-c10-methyl-ester.html
Purity
99.34
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)CCCCCCCCCCBr
Molecular Formula
C12H23BrO2
Molecular Weight
279.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader.J Med Chem. 2019 Dec 12;62 (23) :10897-10911.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
