Fmoc-Asp (OtBu) -OH

Fmoc-Asp (OtBu) -OH (4-tert-Butyl N- (fluoren-9-ylmethoxycarbonyl) -L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp (OtBu) -OH can be used for peptide synthesis[1].

Product Specifications

CAS Number

[71989-14-5]

Product Name Alternative

4-tert-Butyl N- (fluoren-9-ylmethoxycarbonyl) -L-aspartate; Fmoc-L-Asp (OtBu) -OH

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fmoc-asp-otbu-oh.html

Purity

99.89

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)C[C@@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Molecular Formula

C23H25NO6

Molecular Weight

411.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Esquivel J B, et al. Chiral HPLC separation of protected amino acids. Journal of liquid chromatography & related technologies, 1998, 21 (6) : 777-791.|[2]Behrendt R, Huber S, Martí R, White P. New t-butyl based aspartate protecting groups preventing aspartimide formation in Fmoc SPPS. J Pept Sci. 2015 Aug;21 (8) :680-7.