L 158338
L 158338 is an angiotensin II receptor antagonist. L 158338 alleviates acidosis and increases coronary blood flow during the ischemic period and increases coronary blood flow during the reperfusion period. L 158338 can be used to study myocardial injury during ischemia and reperfusion[1].
Product Specifications
CAS Number
133240-38-7
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-158338.html
Smiles
CCCC1=NC2=C(C)C=CN=C2N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5
Molecular Formula
C24H23N7
Molecular Weight
409.49
References & Citations
[1]Werrmann J G, et al. Comparison of effects of angiotensin-converting enzyme inhibition with those of angiotensin II receptor antagonism on functional and metabolic recovery in postischemic working rat heart as studied by [31P] nuclear magnetic resonance[J]. Journal of cardiovascular pharmacology, 1994, 24 (4) : 573-586.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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