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L 158338

L 158338 is an angiotensin II receptor antagonist. L 158338 alleviates acidosis and increases coronary blood flow during the ischemic period and increases coronary blood flow during the reperfusion period. L 158338 can be used to study myocardial injury during ischemia and reperfusion[1].

Product Specifications

CAS Number

133240-38-7

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-158338.html

Smiles

CCCC1=NC2=C(C)C=CN=C2N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5

Molecular Formula

C24H23N7

Molecular Weight

409.49

References & Citations

[1]Werrmann J G, et al. Comparison of effects of angiotensin-converting enzyme inhibition with those of angiotensin II receptor antagonism on functional and metabolic recovery in postischemic working rat heart as studied by [31P] nuclear magnetic resonance[J]. Journal of cardiovascular pharmacology, 1994, 24 (4) : 573-586.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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