SMURF1 Active Human

<strong>SMURF1 Active Human</strong>_x000D_ <strong>Catalog number:</strong> B2019707_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 70 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> E3 ubiquitin ligase SMURF1, KIAA1625, SMAD specific E3 ubiquitin protein ligase 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Xu Y, Shen J, Ran Z. Emerging views of mitophagy in immunity and autoimmune diseases Autophagy. 2020 Jan;16(1):3-17._x000D_ 2: Wrana JL, Attisano L. The Smad pathway Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):5-13._x000D_ 3: Xia Q, Zheng H, Li Y, Xu W, Wu C, Xu J, Li S, Zhang L, Dong L. SMURF1 controls the PPP3/calcineurin complex and TFEB at a regulatory node for lysosomal biogenesis Autophagy. 2024 Apr;20(4):735-751._x000D_ 4: Peng Z, Fang W, Wu B, He M, Li S, Wei J, Hao Y, Jin L, Liu M, Zhang X, Wei Y, Ge Y, Wei Y, Qian H, Zhang Y, Jiang J, Chang Z, Rao Y, Zhang X, Cui CP, Zhang L. Targeting Smurf1 to block PDK1-Akt signaling in KRAS-mutated colorectal cancer Nat Chem Biol. 2025 Jan;21(1):59-70._x000D_ 5: Feng X, Jia Y, Zhang Y, Ma F, Zhu Y, Hong X, Zhou Q, He R, Zhang H, Jin J, Piao D, Huang H, Li Q, Qiu X, Zhang Z. Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth Autophagy. 2019 Jul;15(7):1130-1149._x000D_ 6: Song R, Guo P, Ren X, Zhou L, Li P, Rahman NA, Wołczyński S, Li X, Zhang Y, Liu M, Liu J, Li X. A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer Mol Cancer. 2023 Jul 5;22(1):104._x000D_ 7: Xia Q, Li Y, Han D, Dong L. SMURF1, a promoter of tumor cell progression? Cancer Gene Ther. 2021 Jun;28(6):551-565._x000D_ 8: Roh JD, Hobson R, Chaudhari V, Quintero P, Yeri A, Benson M, Xiao C, Zlotoff D, Bezzerides V, Houstis N, Platt C, Damilano F, Lindman BR, Elmariah S, Biersmith M, Lee SJ, Seidman CE, Seidman JG, Gerszten RE, Lach-Trifilieff E, Glass DJ, Rosenzweig A. Activin type II receptor signaling in cardiac aging and heart failure Sci Transl Med. 2019 Mar 6;11(482):eaau8680._x000D_ 9: Cao Y, Zhang L. A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks Cell Mol Life Sci. 2013 Jul;70(13):2305-17._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37994046">10: Li X, Tao S, Xu Z, Ren Y, Xiang W, He X. SMURF1 activates the cGAS/STING/IFN-1 signal axis by mediating YY1 ubiquitination to accelerate the progression of lupus nephritis Autoimmunity. 2023 Dec;56(1):2281235. </a>_x000D_ _x000D_ <strong>Products Related to SMURF1 Active Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>