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Lipoic acid-d4

Lipoic acid-d4 ((R) - (+) -α-Lipoic acid-d4) is deuterium labeled Lipoic acid. Lipoic acid ((R) - (+) -α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R) - (+) -α-Lipoic acid is more effective than racemic Lipoic acid[1].

Product Specifications

CAS Number

1448263-85-1

Product Name Alternative

(R) - (+) -α-Lipoic acid-d4; R- (+) -Thioctic acid-d4

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Smiles

O=C(CC([2H])(C([2H])(C[C@H]1SSCC1)[2H])[2H])O

Molecular Formula

C8H10D4O2S2

Molecular Weight

210.35

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Nasole E, et al. Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. J Enzyme Inhib Med Chem. 2014 Apr;29 (2) :297-302.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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