Caspase 3/7 Activity Detection Substrate for Flow Cytometry
Selected Variant
E-CK-A483-01
Size: 20 Tests
Product Specifications
Detection Method
Fluorometric method; Flow cytometry
Assay Principle
The Caspase 3/7 Substrates (Green) are based on novel fluorogenic DNA dyes that have been coupled to the caspase 3/7 recognition sequence (DEVD), which is both non-fluorescent and nonfunctional as a DNA dye.When it rapidly crosses cell membranes to enter the cytoplasm and cleaved by caspase 3/7 to form a high-affinity DNA dye that stains the nucleus bright green. Thus, the Caspase 3/7 substrates allow detection of caspase 3/7 activity and visualization of apoptotic nuclear morphology simultaneously.
Sample Type
Cell samples
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2~8°C for 1 year in the dark.
Citation 01
https://pmc.ncbi.nlm.nih.gov/articles/PMC11989111/
Detection Instrument
Flow Cytometer
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