Antibacterial agent 143

Antibacterial agent 143 (Compound 5a) is an antibacterial agent with MICs of 25, 25, 50 and 50 μg/mL against B. subtilis ATCC6633, S. aureus ATCC6538, P. aeruginosa ATCC13525 and E. coli ATCC35218, respectively[1].

Product Specifications

CAS Number

[299405-68-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-143.html

Purity

91.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(CC1=CC=CC=C1)NC2=NC(C3=CC=C(Br)C=C3)=CS2

Molecular Formula

C17H13BrN2OS

Molecular Weight

373.27

Precautions

H302, H315, H319

References & Citations

[1]Li JR, et al. Design and synthesis of thiazole derivatives as potent FabH inhibitors with antibacterial activity. Eur J Med Chem. 2014 Mar 21;75:438-47.