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3-Hydroxyxanthone

3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) . 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression[1].

Product Specifications

CAS Number

3722-51-8

Product Name Alternative

3-Hydroxy-xanthen-9-one

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-hydroxyxanthone.html

Purity

99.68

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1C2=C(OC3=C1C=CC=C3)C=C(O)C=C2

Molecular Formula

C13H8O3

Molecular Weight

212.20

Precautions

H302, H315, H319

References & Citations

[1]Madan B, et al. Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) . Bioorg Med Chem. 2002 Nov;10 (11) :3431-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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