3-Hydroxyxanthone
3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) is a xanthone compound, with . 3-Hydroxyxanthone inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) . 3-Hydroxyxanthone also inhibits TNF-alpha induced ICAM-1 expression[1].
Product Specifications
CAS Number
[3722-51-8]
Product Name Alternative
3-Hydroxy-xanthen-9-one
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/3-hydroxyxanthone.html
Purity
99.68
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OC3=C1C=CC=C3)C=C(O)C=C2
Molecular Formula
C13H8O3
Molecular Weight
212.20
Precautions
H302, H315, H319
References & Citations
[1]Madan B, et al. Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) . Bioorg Med Chem. 2002 Nov;10 (11) :3431-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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