CHI3L1-IN-2
Product Specifications
UNSPSC Description
CHI3L1-IN-2 (Compound 36) is a CHI3L1(YKL-40) inhibitor. CHI3L1-IN-2 inhibits the interaction between CHI3L1 and heparan sulfate (CHI3L1:HSIII), with an IC50 of 26 nM[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/chi3l1-in-2.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](N(C1)C)CN(C2CCN(C3=CC=CC=N3)CC2)[C@H]1CC4=CC=C(C=C4)Cl
Molecular Weight
441.05
References & Citations
[1]Czestkowski W, et al. Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1. J Med Chem. 2024 Mar 14;67(5):3959-3985.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163388/CHI3L1-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163388/
Clinical Information
No Development Reported
CAS Number
2982257-63-4
Available Sizes
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