DDR1-IN-6
DDR1-IN-6 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 9.72 nM. DDR1-IN-6 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 9.7 nM. DDR1-IN-6 has anti-cancer activity[1]. DDR1-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
2416021-47-9
UNSPSC
12352005
Target
Discoidin Domain Receptor
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ddr1-in-6.html
Purity
98.02
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
FC(C1=CC(NC2=NOC3=C2C=CC(C)=C3C#CC4=CN=C5C=CC=NN54)=CC=C1)(F)F
Molecular Formula
C23H14F3N5O
Molecular Weight
433.39
References & Citations
[1]Aleksandr M. Aliper, et al. Kinase inhibitors. WO2020079652A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DDR1
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Pgp9.5 (UCHL-1) (13C4), CF555 conjugate, 0.1mg/mL
