HIV-1 inhibitor-68
HIV-1 inhibitor-68 (compound 26) is a protein kinase C (PKC) activator derivative with reversal activity in HIV-1 latency. HIV-1 inhibitor-68 may be able to eliminate cells latently infected with HIV-1, [1].
Product Specifications
UNSPSC
12352005
Target
HIV; PKC
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics; TGF-beta/Smad
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-68.html
Smiles
CCCCCC/C(CCCCCC)=C1CC(OC/1=O)(CO)COC2=NOC(C)=C2
Molecular Formula
C23H37NO5
Molecular Weight
407.54
References & Citations
[1]Ishii T, Kobayakawa T, Matsuda K, Nigorikawa K, Bolah P, Noborio A, Tsuji K, Ohashi N, Yoshimura K, Nomura W, Mitsuya H, Maeda K, Tamamura H. Discovery of Potent DAG-Lactone Derivatives as HIV Latency Reversing Agents. ACS Infect Dis. 2024 Jun 14;10 (6) :2250-2261.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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