Cyclo (Gly-His)
Cyclo (Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo (Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo (Gly-His) can be used for the research of drug delivery systems[1].
Product Specifications
CAS Number
15266-88-3
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclo-gly-his.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC(N1)=O)[C@@H]1CC2=CN=CN2
Molecular Formula
C8H10N4O2
Molecular Weight
194.19
References & Citations
[1]Kilian G, et al. Anticancer activity of the liposome-encapsulated cyclic dipeptides, cyclo (His-Gly) and cyclo (His-Ala) . Pharmazie. 2013;68 (3) :207-211.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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