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Cyclo (Gly-His)

Cyclo (Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo (Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo (Gly-His) can be used for the research of drug delivery systems[1].

Product Specifications

CAS Number

15266-88-3

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cyclo-gly-his.html

Solubility

10 mM in DMSO

Smiles

O=C(NCC(N1)=O)[C@@H]1CC2=CN=CN2

Molecular Formula

C8H10N4O2

Molecular Weight

194.19

References & Citations

[1]Kilian G, et al. Anticancer activity of the liposome-encapsulated cyclic dipeptides, cyclo (His-Gly) and cyclo (His-Ala) . Pharmazie. 2013;68 (3) :207-211.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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