Oxiracetam

Oxiracetam (ISF2522) is an orally active and a BBB-penetrable cyclic derivative of γ-aminobutyric acid (GABA) . Oxiracetam reaches the hippocampus and cerebral cortex in high concentrations. Oxiracetam can promote cognitive function and regulate inflammatory response, with powerful neuroprotective effects. Oxiracetam can be used in the study of central nervous system diseases[1][2][3] .

Product Specifications

CAS Number

[62613-82-5]

Product Name Alternative

ISF2522

UNSPSC

12352005

Hazard Statement

H315, H319

Target

GABA Receptor; NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Oxiracetam.html

Purity

99.89

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=C(N)CN1C(CC(O)C1)=O

Molecular Formula

C6H10N2O3

Molecular Weight

158.16

Precautions

H315, H319

References & Citations

[1]Li W, et al. (S) -Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Sci Rep. 2017 Aug 30;7 (1) :10052.|[2]Zhang H, et al. Oxiracetam Offers Neuroprotection by Reducing Amyloid β-Induced Microglial Activation and Inflammation in Alzheimer's Disease. Front Neurol. 2020 Jul 17;11:623|[3]Yao XL, et al. Oxiracetam can improve cognitive impairment after chronic cerebral hypoperfusion in rats. Psychiatry Res. 2016 Dec 30;246:284-292.