Colchiceine (Standard)
Colchiceine (Standard) is the analytical standard of Colchiceine. This product is intended for research and analytical applications. Colchiceine is one of several metabolites of the anti-gout medication Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent, and may protect rats from developing liver injury and fibrosis[1][2][3].
Product Specifications
CAS Number
477-27-0
Product Name Alternative
O10-Demethylcolchicine (Standard)
UNSPSC
12352005
Target
Microtubule/Tubulin; Reference Standards
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/colchiceine-standard.html
Smiles
CC(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(O)C2=O)=O
Molecular Formula
C21H23NO6
Molecular Weight
385.41
References & Citations
[1]Rodríguez L, et al. Effects of colchicine and colchiceine in a biochemical model of liver injury and fibrosis. Arch Med Res. 1998;29 (2) :109-116.|[2]Edström A, et al. Inhibition of fast axonal transport and microtubule polymerization in vitro by colchicine and colchiceine. Acta Physiol Scand. 1979;107 (3) :233-237.|[3]Nava-Ocampo AA, et al. Effect of colchiceine and ursodeoxycholic acid on hepatocyte and erythrocyte membranes and liver histology in experimentally induced carbon tetrachloride cirrhosis in rats. Eur J Clin Invest. 1997;27 (1) :77-84.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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