AHR antagonist 2
AHR antagonist 2 (Example 1) is a potent aryl hydrocarbon receptor (AHR) antagonist with IC50s of 885 pM and 2.03 nM for human and mouse AHR. AHR antagonist 2 can be used for the studies of cancers and imbalance of the immune response[1].
Product Specifications
CAS Number
[2338747-54-7]
UNSPSC
12352005
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ahr-antagonist-2.html
Concentration
10mM
Purity
99.30
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=NC(C2=CC=CN=C2)=NC(C3=CC=C(OC(F)(F)F)C=C3)=C1)N[C@@H](C)CO
Molecular Formula
C20H17F3N4O3
Molecular Weight
418.37
References & Citations
[1]Julien LEFRANC, et al. 2-hetarylpyrimidine-4-carboxamides as aryl hydrocarbon receptor anatgonists. WO2019101641A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Brucella suis biovar 1 Urease accessory protein UreG 1 (ureG1)
Recombinant Brucella suis biovar 1 Urease accessory protein UreG 1 (ureG1)
