P-2281
P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P2281 inhibits mTOR activity in colon cancer cells. P-2281 suppresses Dextran sulfate sodium salt (HY-116282C) (DSS) -induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis[1].
Product Specifications
CAS Number
[1112994-35-0]
Product Name Alternative
ACT-179811
UNSPSC
12352005
Hazard Statement
H301, H311, H331, H341
Target
MTOR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p-2281.html
Purity
99.81
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C(NC1=CC=C(N=C1)C#N)=O)Cl
Molecular Formula
C9H8ClN3O
Molecular Weight
209.63
Precautions
H301, H311, H331, H341
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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