Diallyl Trisulfide

Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer[1][2][3][4].

Product Specifications

CAS Number

[2050-87-5]

Product Name Alternative

2-Amino-4-phosphonobutyric acid

UNSPSC

12352100

Hazard Statement

H301

Target

Apoptosis; Bcl-2 Family; Fungal; Influenza Virus; Interleukin Related; Reactive Oxygen Species (ROS) ; SOD

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/diallyl-trisulfide.html

Purity

99.9

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=CCSSSCC=C

Molecular Formula

C6H10S3

Molecular Weight

178.34

Precautions

H301

References & Citations

[1]Pu Liu, et al. Diallyl trisulfide (DATS) effectively induced apoptosis of postharvest diseasePenicillium expansum of citrus. Annals of Microbiology. December 2009, Volume 59, Issue 4, pp 675-679.|[2]Li W, et al. Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo. Acta Biochim Biophys Sin (Shanghai) . 2012 Jul;44 (7) :577-83. |[3]Zhang F, et al. Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice. Int Immunopharmacol. 2015 Dec;29 (2) :326-333.|[4]Ming L, et al. Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo. Virol J. 2021 Aug 19;18 (1) :171.