Xanthine Oxidase Grade II (Lyophilized Powder)

<strong>Xanthine Oxidase Grade II</strong>._x000D_ <table style="height: 581px;" width="452">_x000D_ <tbody>_x000D_ <tr>_x000D_ <td><strong>Catalog #</strong></td>_x000D_ <td>P2010006</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Size</strong></td>_x000D_ <td>100 U and bulk</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Unit Definition</strong></td>_x000D_ <td>Amount of enzyme that produces one micromole of uric acid per minute at pH 7.5 and 25 °C.</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Molecular Weight</strong></td>_x000D_ <td>160 kDa</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Specific Activity</strong></td>_x000D_ <td>16 U/mg</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Purity</strong></td>_x000D_ <td>Uricase, phosphatase &lt; 0.001%</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Storage</strong></td>_x000D_ <td>-20°C. Avoid repeated freeze/thaw cycles.</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Supplied as</strong></td>_x000D_ <td>Brow-red lyophilized powder</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td><strong>Keywords</strong></td>_x000D_ <td>Xanthine oxidase</td>_x000D_ </tr>_x000D_ </tbody>_x000D_ </table>_x000D_ &nbsp;_x000D_ _x000D_ <strong>References</strong>_x000D_ <ul>_x000D_ <li>Xanthine oxidase of Acinetobacter calcoaceticus RL2-M4: Production, purification and characterization. <span class="labs-docsum-authors full-authors">Monika, Sharma NK, Thakur N, Sheetal, Savitri, Bhalla TC.</span> <span class="labs-docsum-journal-citation full-journal-citation">Protein Expr Purif. 2019 Aug;160:36-44.</span></li>_x000D_ <li>Xanthine Oxidase and its Role as Target in Cardiovascular Disease: Cardiovascular Protection by Enzyme Inhibition?<span class="labs-docsum-authors full-authors"> Schuchardt M, Herrmann J, Tolle M, van der Giet M.</span> <span class="labs-docsum-journal-citation full-journal-citation">Curr Pharm Des. 2017;23(23):3391-3404.</span></li>_x000D_ <li>Xanthine oxidase inhibitory activity of new pyrrole carboxamide derivatives: In vitro and in silico studies.<span class="labs-docsum-authors full-authors"> Kıbrız Ä°E, Saçmacı M, Yıldırım Ä°, Abbas Ali Noma S, Taşkın Tok T, Ateş B.</span> <span class="labs-docsum-journal-citation full-journal-citation">Arch Pharm (Weinheim). 2018 Oct;351(10):e1800165.</span></li>_x000D_ <li>Design, synthesis and biological evaluation of 1-hydroxy-2-phenyl-4-pyridyl-1H-imidazole derivatives as xanthineoxidase inhibitors.<span class="labs-docsum-authors full-authors"> Zhang T, Lv Y, Lei Y, Liu D, Feng Y, Zhao J, Chen S, Meng F, Wang S.</span> <span class="labs-docsum-journal-citation full-journal-citation">Eur J Med Chem. 2018 Feb 25;146:668-677.</span></li>_x000D_ <li>Novel XanthineOxidase (XO) inhibitory phenylindanes produced by thermal reaction of caffeic acid.<span class="labs-docsum-authors full-authors"> Fukuyama Y, Hidaka K, Masuda A, Masuda T.</span> <span class="labs-docsum-journal-citation full-journal-citation">Biosci Biotechnol Biochem. 2018 Oct;82(10):1825-1828. </span></li>_x000D_ <li>Design, synthesis, and biological evaluation of 5-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)benzonitrile derivatives as xanthineoxidase inhibitors.<span class="labs-docsum-authors full-authors"> Zhang TJ, Li SY, Zhang Y, Wu QX, Meng FH.</span> <span class="labs-docsum-journal-citation full-journal-citation">Chem Biol Drug Des. 2018 Feb;91(2):526-533.</span></li>_x000D_ <li>In-silico Design and ADMET Studies of Natural Compounds as Inhibitors of XanthineOxidase (XO) Enzyme.<span class="labs-docsum-authors full-authors"> Malik N, Dhiman P, Khatkar A.</span> <span class="labs-docsum-journal-citation full-journal-citation">Curr Drug Metab. 2017;18(6):577-593.</span></li>_x000D_ <li>Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate.<span class="labs-docsum-authors full-authors"> Yamaguchi Y, Matsumura T, Ichida K, Okamoto K, Nishino T.</span> <span class="labs-docsum-journal-citation full-journal-citation">J <a href="https://pubmed.ncbi.nlm.nih.gov/17301077/">Biochem</a>. 2007 Apr;141(4):513-24.</span></li>_x000D_ </ul>