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GFRAL, Mouse (Biotinylated, HEK293, His-Avi)

GFRAL protein, a brainstem-restricted receptor, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. It binds with GDF15, interacts with RET, and activates MAPK- and AKT- signaling pathways. GFRAL acts as a receptor for GDF15 and mediates cellular signaling through RET, requiring prior GDF15 binding. GFRAL Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived GFRAL protein, expressed by HEK293 , with C-Avi, N-His labeled tag.

Product Specifications

Product Name Alternative

GFRAL Protein, Mouse (Biotinylated, HEK293, His-Avi), Mouse, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/gfral-protein-mouse-biotinylated-hek293-his-avi.html

Purity

95.0

Molecular Formula

404194 (Gene_ID) Q6SJE0-1 (Q20-E350) (Accession)

Molecular Weight

Approximately 48-60 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Curated Selection

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