Dilmapimod (tosylate)
Dilmapimod tosylate is a potent p38 MAPK inhibitor that potentially suppresses inflammation in chronic obstructive pulmonary disease.
Product Specifications
CAS Number
937169-00-1
Product Name Alternative
SB-681323 (tosylate) ; GW 681323 (tosylate)
UNSPSC
12352005
Target
Autophagy; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy; MAPK/ERK Pathway
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/dilmapimod-tosylate.html
Smiles
O=S(O)(C1=CC=C(C=C1)C)=O.O=C2C=CC3=C(C4=CC=C(F)C=C4C)N=C(NC(CO)CO)N=C3N2C5=C(F)C=CC=C5F
Molecular Formula
C30H27F3N4O6S
Molecular Weight
628.62
References & Citations
[1]Singh D, et al. A randomized, placebo-controlled study of the effects of the p38 MAPK inhibitor SB-681323 on blood biomarkers of inflammation in COPD patients. J Clin Pharmacol. 2010 Jan;50 (1) :94-100.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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