Dibucaine-d9

Dibucaine-d9 is the deuterium labeled Dibucaine (HY-B0552) .Dibucaine (Cinchocaine) is a sodium channel inhibitor. Dibucaine is a potent SChE inhibitor[1][2].

Product Specifications

CAS Number

[98006-44-1]

Product Name Alternative

Cinchocaine-d9

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

CCN(CC)CCNC(C1=CC(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=NC2=C1C=CC=C2)=O

Molecular Formula

C20H20D9N3O2

Molecular Weight

352.52

References & Citations

[1]Elamin, B., Dibucaine inhibition of serum cholinesterase. J Biochem Mol Biol, 2003. 36 (2) : p. 149-53.|[2]Souto-Padron, T., A.P. Lima, and O. Ribeiro Rde, Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi. Parasitol Res, 2006. 99 (4) : p. 317-20.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.