Perospirone (hydrochloride)
Perospirone hydrochloride (SM-9018) is an orally active antagonist of 5-HT2A receptor (Ki of 0.6 nM) and dopamine D2 receptor (Ki of 1.4 nM) . Perospirone hydrochloride is also a partial agonist of 5-HT1A receptor (Ki of 2.9 nM) . Perospirone hydrochloride is an atypical antipsychotic agent and has the potential for schizophrenic disease research[1][2].
Product Specifications
CAS Number
129273-38-7
Product Name Alternative
SM-9018
UNSPSC
12352005
Hazard Statement
H302
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/perospirone-hydrochloride.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
[H]Cl.O=C([C@@]1([H])[C@]2([H])CCCC1)N(C2=O)CCCCN3CCN(C4=NSC5=C4C=CC=C5)CC3
Molecular Formula
C23H31ClN4O2S
Molecular Weight
463.04
Precautions
H302
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor;5-HT2 Receptor; D1 Receptor; D2 Receptor; mLAG-3; α-1 microglobulin
Available Sizes
Frequently Asked Questions
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