Diclofenac ethyl ester
Diclofenac ethyl ester is the prodrug of Diclofenac (HY-15036), that is encapsulated in polymer micelles in vitro, and released with prolonged circulation time and reduced drug concentrations in the heart and kidneys in vivo[1].
Product Specifications
CAS Number
[15307-77-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/diclofenac-ethyl-ester.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
ClC1=C(C(Cl)=CC=C1)N(C2=C(C=CC=C2)CC(OCC)=O)[H]
Molecular Formula
C16H15Cl2NO2
Molecular Weight
324.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Al-Lawati H, et al., Delivery and Biodistribution of Traceable Polymeric Micellar Diclofenac in the Rat. J Pharm Sci. 2019 Aug;108 (8) :2698-2707.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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