N-Acetylphytosphingosine
Product Specifications
UNSPSC Description
N-Acetylphytosphingosine (NAPS) is a sphingolipid derivative. N-Acetylphytosphingosine induces mitochondria-dependent Apoptosis by activating Bak. N-Acetylphytosphingosine has antitumor activity[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-acetylphytosphingosine.html
Smiles
CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(C)=O
Molecular Weight
359.54
References & Citations
[1]Han Y, et al. N-acetylphytosphingosine-induced apoptosis of Jurkat cells is mediated by the conformational change in Bak. Apoptosis. 2006 Apr;11(4):581-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164263/N-Acetylphytosphingosine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164263/
Clinical Information
Phase 3
CAS Number
21830-28-4
Available Sizes
Curated Selection
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