Phospho-Stat1 (Ser727) Rabbit FITC Conjugate

<strong>Phospho-Stat1 (Ser727) Rabbit FITC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018651_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Huang R, Faratian D, Sims AH, Wilson D, Thomas JS, Harrison DJ, Langdon SP. Increased STAT1 signaling in endocrine-resistant breast cancer PLoS One. 2014 Apr 11;9(4):e94226._x000D_ 2: DeVries TA, Kalkofen RL, Matassa AA, Reyland ME. Protein kinase Cdelta regulates apoptosis via activation of STAT1 J Biol Chem. 2004 Oct 29;279(44):45603-12._x000D_ 3: Zhang S, Morrison JL, Gill A, Rattanatray L, MacLaughlin SM, Kleemann D, Walker SK, McMillen IC. Maternal dietary restriction during the periconceptional period in normal-weight or obese ewes results in adrenocortical hypertrophy, an up-regulation of the JAK/STAT and down-regulation of the IGF1R signaling pathways in the adrenal of the postnatal lamb Endocrinology. 2013 Dec;154(12):4650-62._x000D_ 4: Wu TR, Hong YK, Wang XD, Ling MY, Dragoi AM, Chung AS, Campbell AG, Han ZY, Feng GS, Chin YE. SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nuclei J Biol Chem. 2002 Dec 6;277(49):47572-80._x000D_ 5: Sun W, Xu W, Snyder M, He W, Ho H, Ivashkiv LB, Zhang JJ. The conserved Leu-724 residue is required for both serine phosphorylation and co-activator recruitment for Stat1-mediated transcription activation in response to interferon-gamma J Biol Chem. 2005 Dec 23;280(51):41844-51._x000D_ 6: Koo MY, Park J, Lim JM, Joo SY, Shin SP, Shim HB, Chung J, Kang D, Woo HA, Rhee SG. Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6269-74._x000D_ 7: Lu C, Pelech S, Zhang H, Bond J, Spach K, Noubade R, Blankenhorn EP, Teuscher C. Pertussis toxin induces angiogenesis in brain microvascular endothelial cells J Neurosci Res. 2008 Sep;86(12):2624-40._x000D_ 8: Rosner D, Stoneman V, Littlewood T, McCarthy N, Figg N, Wang Y, Tellides G, Bennett M. Interferon-gamma induces Fas trafficking and sensitization to apoptosis in vascular smooth muscle cells via a PI3K- and Akt-dependent mechanism Am J Pathol. 2006 Jun;168(6):2054-63._x000D_ 9: Liu X, Ye L, Bai Y, Mojidi H, Simister NE, Zhu X. Activation of the JAK/STAT-1 signaling pathway by IFN-gamma can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG J Immunol. 2008 Jul 1;181(1):449-63._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/38388542">10: Jia L, Jiang Y, Wu L, Fu J, Du J, Luo Z, Guo L, Xu J, Liu Y. Porphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis Nat Commun. 2024 Feb 22;15(1):1617. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Stat1 (Ser727) Rabbit FITC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>