Alinidine (hydrobromide)

Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects[1][2].

Product Specifications

CAS Number

[71306-36-0]

Product Name Alternative

St-567 (hydrobromide)

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/alinidine-hydrobromide.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=CC=CC(Cl)=C1N(CC=C)C2=NCCN2.Br

Molecular Formula

C12H14BrCl2N3

Molecular Weight

351.07

References & Citations

[1]Snyders DJ, et al. Alinidine modifies the pacemaker current in sheep Purkinje fibers. Pflugers Arch. 1987;410 (1-2) :83-91.|[2]J L Challinor-Rogers, et al. Antiischemic and antiarrhythmic activities of some novel alinidine analogs in the rat heart. J Cardiovasc Pharmacol. 1997 Apr;29 (4) :499-507.