FXIIa-IN-3
FXIIa-IN-3 (Compound 8) is a potent and selective Factor XIIa (FXIIa) inhibitor, with an IC50 of 0.045 μM. FXIIa-IN-3 also exhibits a substantial margin of selectivity against related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 can be used for the research of thromboembolic diseases[1].
Product Specifications
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxiia-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C(C2=CC(OC)=C(OC)C(OC)=C2)=O)C(N)=N1)OC
Molecular Formula
C14H16N4O6
Molecular Weight
336.30
References & Citations
[1]Woodland M L D, et al. New Triazole-Based Potent Inhibitors of Human Factor XIIa as Anticoagulants. ACS Omega. 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Cytochrome C (Mitochondrial Marker) (rCYCS/1010), 1mg/mL
Bcl-2 (100/D5 + 124), Biotin conjugate, 0.1mg/mL
