RA-V

RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways[1].

Product Specifications

CAS Number

[64725-24-2]

UNSPSC

12352005

Target

C-Myc; Notch; Wnt

Type

Natural Products

Related Pathways

Apoptosis; Neuronal Signaling; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ra-v.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C2C=C1OC3=CC=C(C[C@@]4(N(C([C@H](C)NC([C@@H](N(C([C@H](C)NC([C@@H](C)NC([C@]([H])(C2)N(C)C4=O)=O)=O)=O)C)CC5=CC=C(OC)C=C5)=O)=O)C)[H])C=C3

Molecular Formula

C40H48N6O9

Molecular Weight

756.84

References & Citations

[1] Premalatha Balachandran, et al. Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia. Molecules. 2021 Jan 31;26 (3) :735.