2,4,6-Trihydroxybenzaldehyde

2,4,6-Trihydroxybenzaldehyde is an orally active NF- B inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity[1][2][3].

Product Specifications

CAS Number

[487-70-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/2-4-6-trihydroxybenzaldehyde.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=CC1=C(O)C=C(O)C=C1O

Molecular Formula

C7H6O4

Molecular Weight

154.12

Precautions

H315, H319, H335

References & Citations

[1]Kim KN, et al. 2,4,6-Trihydroxybenzaldehyde, a potential anti-obesity treatment, suppressed adipocyte differentiation in 3T3-L1 cells and fat accumulation induced by high-fat diet in C57BL/6 mice. Environ Toxicol Pharmacol. 2015 Mar;39 (2) :962-8.|[2]Marton A, et al. Vanillin Analogues o-Vanillin and 2,4,6-Trihydroxybenzaldehyde Inhibit NFĸB Activation and Suppress Growth of A375 Human Melanoma. Anticancer Res. 2016 Nov;36 (11) :5743-5750.|[3]Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58 (9) :5320-7.