SIAH1 rabbit pAb
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Gene ID
6477
UniProt
Q8IUQ4
Cellular Locus
Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
Host
Rabbit
Species Reactivity
Human,Rat
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human SIAH1 AA range: 157-207
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1: 500-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13109-1.pdf
Subcellular Location
Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
Gene ID (Human)
6477
SwissProt (Human)
Q8IUQ4
Available Sizes
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