DL-Aspartic acid-d3

DL-Aspartic acid-d3 is the deuterium labeled L-Aspartic acid. L-Aspartic aicd is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd commonly used in the study of inflammatory conditions[1][2][3].

Product Specifications

CAS Number

[14341-75-4]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Purity

99.56

Solubility

1 M NaOH : 100 mg/mL (ultrasonic; adjust pH to 11 with 1 M NaOH)

Smiles

NC(C([2H])([2H])C(O)=O)([2H])C(O)=O

Molecular Formula

C4H4D3NO4

Molecular Weight

136.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73 (3) :1206-11.|[2]Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly (L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23 (4) :397-406.|[3]Su G, et al. Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub. Redox Biol. 2024 May;71:103112.