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6β-Prostaglandin I1

Product Specifications

Product Name Alternative

6β-PGI1

UNSPSC Description

6β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID50 (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection)[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6β-prostaglandin-i1.html

Solubility

10 mM in DMSO

Smiles

CCCCC[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O[C@H](C2)CCCCC(O)=O

Molecular Weight

354.48

References & Citations

[1]Kauffman GL Jr, et al. Effects of prostacyclin and a stable analogue, 6-beta-PGI1, on gastric acid secretion, mucosal blood flow, and blood pressure in conscious dogs. Gastroenterology. 1979 Dec;77(6):1301-6. PMID: 387511.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130522/6β-Prostaglandin-I1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130522/

Clinical Information

No Development Reported

CAS Number

62770-50-7

Available Sizes

Curated Selection

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